Google loses antitrust case over search (2 minute read)
A federal judge has ruled that Google illegally held a monopoly in search and text advertising. Google was found to have violated Section 2 of the Sherman Act, which outlaws monopolies. The ruling is the first anti-monopoly decision against a tech company in decades. Google plans to appeal the ruling.
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Chrome's Manifest V3, and its changes for ad blocking, are coming real soon (2 minute read)
Chrome is preparing to make Manifest V3 compulsory for extensions that want to run on its platform. Some users recently reported seeing warnings telling them that certain extensions may no longer be supported. V2 extensions started being disabled in early June on the Beta, Dev, and Canary update channels. Users will still be able to manually re-enable V2 extensions for a short time.
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Science & Futuristic Technology
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A primer on the current state of longevity research (19 minute read)
This article takes a look at how far the field of aging research has progressed since 2021. Nothing particularly useful has come from sirtuin-focused therapies and this is unlikely to change. The increase in longevity-focused research institutions/grant programs/startups hasn't led to much progress, but it's still very early. Cellar reprogramming has shown promise in animal studies, but no therapies have reached clinical trials yet. There's still a lot we don't know about biological clocks - everyday consumers should probably avoid getting their biological age tested. While epigenetic clocks seem to be useful, their interpretation is a bit complicated.
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Path to precision: Targeted cancer drugs go from table to trials to bedside (18 minute read)
There are now many targeted therapies and new techniques in the pipeline for treating various types of cancer. This article looks at the history of targeted cancer treatments to see how far the science has come. It took many preclinical studies, genetic sequencing advances, and other breakthroughs to get where we are now. The success of current treatments would not have been possible without all of the research legwork and basic science over the past few decades.
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Programming, Design & Data Science
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How Postgres stores data on disk (35 minute read)
Databases contain some immensely powerful and clever abstractions. They aren't that complicated - most of the complexity in them comes from edge cases, often around concurrency. This article looks at how databases store data on disk, with a focus on PostgreSQL. It also provides resources for further research. Understanding how databases work is useful for fine-tuning performance and data recovery.
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How I program in 2024 (7 minute read)
This article shares a developer's perspective on how to program durable things. The developer found that he ended up with much better programs by giving up tests and versions. Building durably for lots of people is hard - it's much better to focus on a core set of people and features. Overuse of the same tools creates technical debt, making programs unnecessarily complex, less durable, and harder to change when the context shifts.
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Cookie banners show everything that's wrong with the EU (2 minute read)
Billions of dollars have been spent on cookie banner compliance just to annoy users with no material improvement to their privacy. The EU has no mechanism for self-correcting legislative failures. Europe needs to rethink how it legislates tech as the amount of squandered potential is tragic. Very little innovation is happening in Europe and when it does, it's usually shipped to the US or elsewhere as soon as it's ready to make a real impact on the world.
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OpenAI tempers expectations with less bombastic, GPT-5-less DevDay this fall (4 minute read)
OpenAI is changing the format of its DevDay conference to a series of on-the-road developer engagement sessions. It won't be releasing its next major flagship model during the event. The conference will focus on educating developers about what's available in showcasing dev community stories. The DevDay events will take place in San Francisco on October 1, London on October 30, and Singapore on November 21. Registration costs $450 - applications close on August 15.
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Dan Ni & Stephen Flanders
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